The gift, announced Sept. 15, is one of the largest to a healthcare institution in American history, the hospital's parent, Providence St. Joseph Health said in a press release.
In March, the hospital announced that Phil and Penny Knight were making a second $75 million donation to advance cardiac care at the hospital and at the Providence Heart Institute, which share a campus. That donation brought the Knights' gifts to the heart institute to almost $200 million over the last 10 years.
The most recent gift will help fund Oregon's first women's hospital, additional cardiovascular care, clinical research and innovation initiatives, workforce and physician development, and patient support services that improve access and continuity of care.
"Penny and I have always believed that real breakthroughs come from people willing to take on the toughest challenges," Phil Knight said in the release. "Providence has shown that kind of ambition in cardiovascular care, and we see the same opportunity to do something truly distinctive for women's health. We're proud to invest in teams that will change what's possible for communities across Oregon and beyond."
Erik Wexler, president and CEO of Providence, said in the release that the gift marked a "significant and transformational milestone" and enables Providence to enhance access and support for patients as well as create new possibilities in women's health and cardiovascular care. "I join everyone at Providence in extreme gratitude to Phil and Penny Knight for demonstrating their confidence in our caregivers, our leaders and our mission," Wexler said.
Dr. Dan Oseran, the Providence Heart Institute's medical director, said: "All of us at Providence are deeply grateful for Phil and Penny's commitment to better health and wellness, and energized by what lies ahead."